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Pair carbohydrates with protein or healthy fats to slow absorption Front-load vegetables in meals before starchy components Avoid liquid calories and sweetened beverages Eat slowly to allow fullness signals to register Choose smaller, more frequent meals to reduce post-meal spikes Meal timing can influence glucose outcomes

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Additionally, functionalized LNPs incorporating peptides that target receptors overexpressed on brain ECs and neurons—such as RVG29, T7, AP2, and mApoE—have been demonstrated to enhance mRNA transfection in the mouse brain, while reducing hepatic accumulation following systemic administration [164]